RESEARCH 2018-04-12T19:49:01+00:00

Our Research


  • Longitudinal characterization of cognitive changes in a transgenic rat model of Huntington’s disease.
  • Neural network dynamics in association with the onset and progression of Huntington’s Disease in a transgenic mouse model.
  • Endocannabinoid modulation of goal-directed behavior.
  • Endocannabinoid modulation of learning behavior through process of negative reinforcement.
  • The role of cannabinoid receptor activity in aversive learning behavior (in collaboration with Carl Lupica).
  • Dynamic changes in the size of dopamine neurons following drugs of abuse (in collaboration with Eric Nestler).
  • Endocannabinoid signaling mechanisms in schizophrenia (in collaboration with Patricio O’Donnell).
  • Neural mechanisms of reward (in collaboration with Roy Wise).
  • Serotonin/dopamine interactions (in collaboration with Marisela Morales).
  • The role of cannabinoid receptor activation in reward prediction (in collaboration with Geoffrey Schoenbaum).
  • The neuroeconomic impact of CB1 receptor blockade (in collaboration with Peter Shizgal).
  • The role of subsecond dopamine release in observational learning (in collaboration with Matt Roesch).


  • Optogenetics
  • Chemogenetics
  • Iontophoresis
  • Intra-cranial self-stimulation
  • Drug self-administration
  • Genetically encoded calcium indicators
  • Calcium imaging neuron microscopy
  • Fast-scan cyclic voltammetry (FSCV)
  • Ensemble (multiple single-unit) recordings
  • Combined FSCV and single-unit electrophysiology